James Mitchell, PhD

Assistant Professor at the University of Colorado Anschutz. Focusing on Human-Computer Interaction, Clinical Decision Support, and Artificial Intelligence.

Dr. James Mitchell

About Me

I am an Assistant Professor in the Department of Biomedical Informatics at the University of Colorado Anschutz. My research sits at the intersection of human-computer interaction, clinical decision support, and artificial intelligence, designing user-centred systems that improve how clinicians access and act on information at the point of care.

I completed my PhD at Keele University, working in partnership with University Hospital North Midlands NHS Trust as part of a funded project to develop bedside mobile clinical guidelines.

Current projects include LLM-based feedback systems for clinical environments, privacy-preserving NLP for clinical acronym disambiguation, drug-drug interaction decision support, and wearable-based anxiety detection. I collaborate with Stanford, University of Utah, Vanderbilt, Keele University, and more.

Research Projects

ClarifAI

An LLM-based system for collecting structured AI feedback in hard-to-reach clinical environments, enabling continuous improvement of decision-support tools at the point of care.

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PLACID

A privacy-preserving LLM framework for inferring and disambiguating clinical acronyms at scale, improving EHR readability and reducing documentation ambiguity.

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Bedside Clinical Guidelines

A user-centred mobile application delivering evidence-based clinical guidelines at the point of care, developed in close collaboration with University Hospital North Midlands NHS Trust.

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Selected Publications

PLACID: Privacy-preserving Large language models for Acronym Clinical Inference and Disambiguation

Aithal, Kotz & Mitchell (2026) — arXiv preprint

Large Language Models Clinical NLP
arXiv:2603.23678

Navigating Complexity: Enhancing Pediatric Diagnostics With Large Language Models

Mitchell & Bennett (2024) — Pediatric Critical Care Medicine, 25(6):577–580

Large Language Models Pediatric Care
DOI Link

A Rapid Review on Current and Potential Uses of Large Language Models in Nursing

Hobensack et al. (2024) — International Journal of Nursing Studies, 154, 104753

Large Language Models Nursing Informatics
DOI Link

Artificial Intelligence-Based Technologies in Nursing: A Scoping Literature Review of the Evidence

von Gerich et al. (2022) — International Journal of Nursing Studies

AI in Nursing Literature Review
DOI Link